DIS 2005 brought together 280 experimentalists and theorists at the Frank Lloyd Wright Monona Terrace Convention Center in Madison, Wisconsin, U.S.A. The workshop began April 27, 2005 and ran through May 1, 2005. The workshop format involved plenary sessions with review talks and parallel working group sessions with shorter contributions.

The 2005 workshop was hosted by the High Energy Physics group of the University of Wisconsin–Madison Physics Department. The workshop was followed by the 2005 Phenomenology Symposium May 2-4 at the University of Wisconsin–Madison.